RGT - Regulatory Genomics Toolbox


RGT is an open source Python 3.6+ library for analysis of regulatory genomics. It is programmed in an oriented object fashion and its core classes provide functionality for handling regulatory genomics data.

This project is developed and maintained by Institute for Computational Genomics , RWTH University Hostpital. If you have any questions/comments/problems, please open an issue on Github.

The toolbox is made of a core library and several tools:

  • HINT: ATAC-seq/DNase-seq footprinting method

  • Motif Analysis: TBFS match and enrichment

  • THOR: ChIP-Seq differential peak caller

  • TDF: DNA/RNA triplex domain finder

  • RGT-Viz: Visualization tool